Article

Role of ICI-182,780 as a Repurposed Drug to reduce Glioblastoma Stemness sustained by Estrogen signaling: First evidence of GLI-1 as co-activator of ERα

2026-08-31

Abstract excerpt

<title>Abstract</title> <bold>Background</bold> Glioblastoma is the most aggressive primary brain tumor in adults, and its poor clinical outcome is largely driven by glioblastoma stem cells (GSCs), which promote tumor progression, therapeutic resistance, and recurrence. Although the renin-angiotensin system has been implicated in GBM progression, the molecular mechanisms linking Angiotensin II (Ang II) sign...

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Literature Corpus work: 55b26236-d361-5f6b-ba95-92b5ec7c9f88
DOI: 10.21203/rs.3.rs-10581000/v1

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Role of ICI-182,780 as a Repurposed Drug to reduce Glioblastoma Stemness sustained by Estrogen signaling: First evidence of GLI-1 as co-activator of ERαDOI 10.21203/rs.3.rs-10581000/v1Read

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