Article

HRI Inhibition by Hemin as a Novel Targeted Therapy for Glioblastoma via the Integrated Stress Response

2024-04-09

Abstract excerpt

The treatment of glioblastoma (GBM), a highly malignant brain tumor, is critically hindered by the ineffectiveness of current modalities such as surgery, radiation, and chemotherapy. These traditional methods fail to completely remove the tumor mass and lack the ability to discriminate between cancerous and normal brain cells, often resulting in collateral damage to healthy tissue and recurrence of the disease. Th...

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Literature Corpus work: f4ab18d9-9104-57e2-8210-8d7021126779
DOI: 10.21203/rs.3.rs-4196062/v1

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