Article

Propranolol Inhibits the Proliferation of Human Glioblastoma Cell Lines Through Notch1 and Hes1 Signaling System

2021-04-01

Abstract excerpt

<title>Abstract</title> <p>PurposeThe anti-tumor effect of the beta-adrenergic receptor antagonist propranolol in breast cancer is well known; however, its activity in glioblastoma is not well-evaluated. The Notch-Hes pathway is known to regulate cell differentiation, proliferation, and apoptosis. We investigated the effect of propranolol to human glioblastoma cell lines, and the role of Notch and Hes signaling i...

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Literature Corpus work: 1132221c-bcc7-5834-96bd-f19a74c43c31
DOI: 10.21203/rs.3.rs-378415/v1

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