Article

Comprehensive characterization of transcript diversity at the human <i>NODAL</i> locus

2018-01-25

Abstract excerpt

NODAL , a morphogen belonging to the transforming growth factor beta (TGβ) superfamily, is essential during embryogenesis where it induces axis formation and left-right asymmetry. NODAL is also required for the maintenance of human embryonic stem cell pluripotency, and emerges in many cancer types concomitant with metastasis and therapy resistance. Several enhancer elements have been shown to regulate mouse Noda...

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Literature Corpus work: 558662f9-762b-5034-9ec0-69aa8706886d
DOI: 10.1101/254409

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