Article
Roles of TGF-beta in hepatic fibrosis
2002-01-01
Abstract excerpt
TGF-beta has multiple profibrogenic but also anti-inflammatory and immunosuppressive effects. The balance of these actions is required for maintaining tissue homeostasis and an aberrant expression of TGF-beta is involved in a number of disease processes in the liver. In addition to its fibrogenic action leading to transdifferentiation of hepatic stellate cells into myofibroblasts, TGF-beta is also an important neg...
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Identifiers and source
- Literature Corpus work
- 557cb677-0490-5958-9fbf-7be1dc6f06fa
- DOI
- 10.2741/gressner