Article
TGF-β signaling in liver and gastrointestinal cancers.
Cancer letters - 1 Sept 2016
Katz L H, Likhter M, Jogunoori W, Belkin M, Ohshiro K, Mishra L
Abstract excerpt
Transforming Growth Factor-β (TGF-β) plays crucial and complex roles in liver and gastrointestinal cancers. These include a multitude of distinct functions, such as maintaining stem cell homeostasis, promoting fibrosis, immune modulating, as a tumor suppressor and paradoxically, as a tumor progressor. However, key mechanisms for the switches responsible for these distinct actions are poorly understood, and remain...
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