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The dichotomous role of TGF-β in controlling liver cancer cell survival and proliferation

1 Sept 2020

Abstract excerpt

Hepatocellular carcinoma (HCC) is the major form of primary liver cancer and one of the most prevalent and life-threatening malignancies globally. One of the hallmarks in HCC is the sustained cell survival and proliferative signals, which are determined by the balance between oncogenes and tumor suppressors. Transforming growth factor beta (TGF-β) is an effective growth inhibitor of epithelial cells including...

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PMID: 33339765
DOI: 10.1016/j.jgg.2020.09.005

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