Article

Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer

2019-10-02

Abstract excerpt

Metastasis is the major cause of cancer death. An increased level of circulating tumor cells (CTCs), metastatic cancer cells that have intravasated into the circulatory system, is particularly associated with colonization of distant organs and poor prognosis. However, the key factors required for tumor cell dissemination and colonization remain elusive. We found that high expression of Desmoglein2 (DSG2), a compon...

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Literature Corpus work: 557860f3-855e-5869-bbfa-71ba16887bfb
DOI: 10.1101/790519

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