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Article

Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing.

Neuroscience - 1 Dec 2020

Thiry Louise, Hamel Regan, Pluchino Stefano, Durcan Thomas, Stifani Stefano

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) offer the opportunity to generate specific cell types from healthy and diseased individuals, allowing the study of mechanisms of early human development, modelling a variety of human diseases, and facilitating the development of new therapeutics. Human iPSC-based applications are often limited by the variability among iPSC lines originating from a single donor, as well...

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Identifiers

PMID: 32380268
DOI: 10.1016/j.neuroscience.2020.04.041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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