Article

A Computational Pipeline for Physiologically Informed Calibration of Ligand Reaction-Diffusion Models Using High-Throughput Sequencing

2025-08-29

Abstract excerpt

All physiological processes fundamentally rely on continuous cellular cross-talk to maintain organization and ensure proper function. Among the various modes of cellular communication, ligand-mediated chemical signaling, in which a ligand is secreted by one cell, diffuses through the extracellular environment, and binds to a receptor on another (or the same) cell to elicit a downstream response, is arguably the mo...

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Literature Corpus work: 5513b4c2-4593-54eb-842c-3b35c940cde5
DOI: 10.1101/2025.08.25.672053

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