Article

Artificial neural networks enable genome-scale simulations of intracellular signaling

2021-09-24

Abstract excerpt

Mammalian cells adapt their functional state in response to external signals in form of ligands that bind receptors on the cell-surface. Mechanistically, this involves signal-processing through a complex network of molecular interactions that govern transcription factor (TF) activity patterns. Computer simulations of the information flow through this network could help predict cellular responses in health and dise...

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Literature Corpus work: 40d44914-9106-5192-999c-cbcef466171e
DOI: 10.1101/2021.09.24.461703

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