Article
In silico identification of potential therapeutic targets in the TGF-β signal transduction pathway.
Molecular bioSystems - 4 Mar 2014
Nicklas Daniel, Saiz Leonor
Abstract excerpt
The transforming growth factor-β (TGF-β) superfamily of cytokines controls fundamental cellular processes, such as proliferation, motility, differentiation, and apoptosis. This fundamental role is emphasized by the widespread presence of mutations of the core components of the TGF-β signal transduction pathway in a number of human diseases. Therefore, there is an increasing interest in the development of...
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