Article

Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a commonality across autoantibody-associated diseases

2021-03-08

Abstract excerpt

Elevated N-linked glycosylation of immunoglobulin G variable regions (IgG-V N-Glyc ) is an emerging molecular phenotype associated with autoimmune disorders. To test the broader specificity of elevated IgG-V N-Glyc , we studied patients with distinct subtypes of myasthenia gravis (MG), a B cell-mediated autoimmune disease. Our experimental design included adaptive immune receptor repertoire sequencing to quantif...

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Literature Corpus work: 54f854f7-8a37-5486-a090-bd8cbc91f729
DOI: 10.1101/2021.03.06.434199

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