Article

Protein structure, a genetic constraint on glycosylation

2024-05-15

Abstract excerpt

Unlike DNA, RNA, and protein biosynthesis, dogma describes glycosylation as primarily determined by intrinsic cellular limitations, such as glycosyltransferase expression and precursor availability. However, this cannot explain the commonly-observed differences between glycans on the same protein. By examining site-specific glycosylation on diverse human proteins, we detected associations between protein structure...

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Literature Corpus work: ebeb04e6-10ef-5116-bfbd-eae360888cf9
DOI: 10.1101/2024.05.15.594261

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