Article
IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.
The Journal of experimental medicine - 26 Aug 2013
Saenz Steven A, Siracusa Mark C, Monticelli Laurel A, Ziegler Carly G K, Kim Brian S, Brestoff Jonathan R, Peterson Lance W, Wherry E John, Goldrath Ananda W, Bhandoola Avinash, Artis David
Abstract excerpt
The predominantly epithelial cell-derived cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) can promote CD4(+) Th2 cell-dependent immunity, inflammation, and tissue repair at barrier surfaces through the induction of multiple innate immune cell populations. IL-25 and IL-33 were previously shown to elicit four innate cell populations, named natural helper cells, nuocytes, innate type 2 helper cells,...
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