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Group 2 Innate Lymphoid Cells: A Double-Edged Sword in Cancer?

20 Nov 2020

Abstract excerpt

Group 2 Innate Lymphoid Cells (ILC2s) belong to the family of helper ILCs which provide host defense against infectious agents, participate in inflammatory responses and mediate lymphoid organogenesis and tissue repair, mainly at the skin and mucosal level. Based on their transcriptional, phenotypic and functional profile, ILC2s mirror the features of the adaptive CD4+ Th2 cell subset, both contributing to the...

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PMID: 33233582
DOI: 10.3390/cancers12113452

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