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<i>Helicobacter pylori</i> genome aggregation database reveals complex evolutionary forces shaping its genomic landscape and clinical impact in East Asia

2025-08-15

Abstract excerpt

We assembled HPgnomAD, a comprehensive global genome aggregation database of Helicobacter pylori ( H. pylori ) featuring 7,544 high-quality genomes from 278 populations, along with the first species-wide haplotype reference panel for genotype imputation. The panel provides high accuracy across diverse H. pylori populations, including those from low-coverage data, and is openly accessible with integrated analysi...

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Literature Corpus work
54e207c2-d2eb-573a-81a0-b6b3f93823ba
DOI
10.1101/2025.08.13.669870
Open publication

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<i>Helicobacter pylori</i> genome aggregation database reveals complex evolutionary forces shaping its genomic landscape and clinical impact in East AsiaDOI 10.1101/2025.08.13.669870
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