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Helicobacter pylori Genome Aggregation Database reveals complex evolutionary forces shaping its genomic landscape and clinical impact in East Asia

2025-08-28

Abstract excerpt

<title>Abstract</title> We assembled HPgnomAD, a comprehensive global genome aggregation database of Helicobacter pylori (H. pylori) featuring 7,544 high-quality genomes from 278 populations, along with the first species-wide haplotype reference panel for genotype imputation. The panel provides high accuracy across diverse H. pylori populations, including those from low-coverage data, and is openly accessible...

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Literature Corpus work: 4424a72a-7f1c-5dd2-bcf1-ec8845b87f25
DOI: 10.21203/rs.3.rs-7366252/v1

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