Global Population Structure, Virulence Factors and Antibiotic Resistance of Helicobacter pylori : A Pooled Analysis of 4067 Isolates From 76 Countries

Abstract excerpt

BACKGROUND: Helicobacter pylori (H. pylori) is a common pathogen that has co-evolved with the human host for approximately 100,000 years; however, our understanding of its population structure remains limited. Furthermore, the detailed characteristics of its virulence factors and antibiotic resistance for H. pylori are not yet fully elucidated. METHODS: In this study, we curated a global genome dataset of 4067 H....