A 500-year tale of co-evolution, adaptation, and virulence: Helicobacter pylori in the Americas.

doi:10.1038/s41396-020-00758-0

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Article

A 500-year tale of co-evolution, adaptation, and virulence: Helicobacter pylori in the Americas.

The ISME journal - 1 Jan 2021

Muñoz-Ramirez Zilia Y, Pascoe Ben, Mendez-Tenorio Alfonso, Mourkas Evangelos, Sandoval-Motta Santiago, Perez-Perez Guillermo, Morgan Douglas R, Dominguez Ricardo Leonel, Ortiz-Princz Diana, Cavazza Maria Eugenia, Rocha Gifone, Queiroz Dulcienne M M, Catalano Mariana, Palma Gerardo Zerbetto De, Goldman Cinthia G, Venegas Alejandro, Alarcon Teresa, Oleastro Monica, Vale Filipa F, Goodman Karen J, Torres Roberto C, Berthenet Elvire, Hitchings Matthew D, Blaser Martin J, Sheppard Samuel K, Thorell Kaisa, Torres Javier

Abstract excerpt

Helicobacter pylori is a common component of the human stomach microbiota, possibly dating back to the speciation of Homo sapiens. A history of pathogen evolution in allopatry has led to the development of genetically distinct H. pylori subpopulations, associated with different human populations, and more recent admixture among H. pylori subpopulations can provide information about human migrations. However,...

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PMID: 32879462
DOI: 10.1038/s41396-020-00758-0
PMCID: PMC7853065

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