Article

Comparison of Anchor- and Distribution-Based Methods for Estimating Thresholds of Meaningful Within-Patient Change Using Simulated PROMIS PF 20a Data Under Various Joint Distribution Characteristic Conditions

2021-05-27

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>To compare the performance of anchor-based and distribution-based methods for estimating thresholds of meaningful within-patient change of clinical outcome assessments in conditions reflecting data characteristics of small- to medium-sized clinical trials.<bold>Methods</bold>Data sets were generated from the joint distributions of the PROMIS PF 20a T-score changes an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 54c9684e-6fd9-5488-abf2-7ed2c5e1f24b
DOI: 10.21203/rs.3.rs-381557/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparison of Anchor- and Distribution-Based Methods for Estimating Thresholds of Meaningful Within-Patient Change Using Simulated PROMIS PF 20a Data Under Various Joint Distribution Characteristic ConditionsDOI 10.21203/rs.3.rs-381557/v1Read

Assessing systematic measurement changes in single-wave study data: a simulation studySemantic proximity Read

Guidance for defining outcomes in clinical trialsSemantic proximity Read

Exact Probability Distribution for the ROC Area Under CurveSemantic proximity Read

Comparison of statistical methods for the analysis of patient-reported outcomes (PROs), particularly the Short-Form 36 (SF-36), in randomised controlled trials (RCTs) using standardised effect size (SES): an empirical analysisSemantic proximity Read

The p–fr–nb triplet: a unified framework for statistical fragility and robustness across clinical study designsSemantic proximity Read

The Call for Progress in Evidence-Based MedicineSemantic proximity Read

When scalar endpoints cannot identify multidomain stabilization: estimand-aligned trajectory summaries for chronic longitudinal trialsSemantic proximity Read

The Effect of Dichotomization of Skewed Adjustment Covariates in the Analysis of Clinical TrialsSemantic proximity Read

Meta-Analytical Approaches to Ordinal Outcome Data in Clinical Interventional Studies: A Scoping Review with Reproducible ResearchSemantic proximity Read

Parametric analysis and normality assumption in phase 3 trials with small sample sizesSemantic proximity Read

Review of calculation of conditional power, predictive power and probability of success in clinical trials with continuous, binary and time-to-event endpointsSemantic proximity Read

The Formulation of Minimal Clinically Important Differences in the Quality of Life Instrument for Patients with Chronic Renal Failure (QLICD-CRF) Based on Combinations of Anchor-Based and Distribution-Based MethodsSemantic proximity Read