Article

The p–fr–nb triplet: a unified framework for statistical fragility and robustness across clinical study designs

2025-11-21

Abstract excerpt

Clinical studies commonly report p-values but rarely quantify how stable those p-values are or how far the observed data lie from the point representing no effect. This study introduces a unified framework that evaluates statistical significance, fragility, and neutrality distance across three standard clinical data structures: single-arm binomial outcomes, two-arm binary outcomes, and continuous two-group outcome...

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Literature Corpus work: ac64a363-6b52-5e21-bb86-3e3cc70ebf8d
DOI: 10.1101/2025.11.20.25340684

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