Article

Parametric analysis and normality assumption in phase 3 trials with small sample sizes

2024-06-03

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<title>Abstract</title> <p>Background In studies with small sample sizes, the use of nonparametric methods is generally recommended for statistical analysis. However, various studies continue to employ parametric analysis without verifying the assumption of a normal distribution. Objectives To assess the current utilization of parametric and nonparametric methods for primary outcomes, as well as the reporting o...

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Literature Corpus work: 738228cb-621c-5d40-808e-5f7a437906d3
DOI: 10.21203/rs.3.rs-4447330/v1

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