Article

Assessing systematic measurement changes in single-wave study data: a simulation study

2026-05-21

Abstract excerpt

<title>Abstract</title> <p>Background: Observational and clinical studies involve sequential data acquisi tion over extended calendar periods. Systematic changes across the measurement sequence may compromise the validity of scientific findings. In contrast to bio logical associations, however, typically few assumptions can be made about the form, timing, or magnitude of such changes, and practical guidance for t...

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Literature Corpus work: ca9e9bd3-3177-52ba-a5e0-15d695a6df3c
DOI: 10.21203/rs.3.rs-9415526/v1

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