Article

Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes

2025-05-09

Abstract excerpt

<h4>ABSTRACT</h4> The immune mechanisms induced by the Bacillus Calmette-Guérin (BCG) vaccine, and the subset of which mediate protection against tuberculosis (TB), remain poorly understood. This is further complicated by difficulties to verify vaccine-induced protection in humans. Although research in animal models, namely mice and non-human primates (NHPs), has begun to close this knowledge gap, discrepancies i...

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Literature Corpus work: bf50873b-d93c-5880-9269-8982c3706707
DOI: 10.1101/2025.05.05.652268

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