Article
Genomic subtypes of cutaneous melanoma have distinct metabolic profiles: A single-cell transcriptomic analysis.
Archives of dermatological research - 1 Dec 2023
Diaz Michael J, Tran Jasmine T, Choo Zi-Ning, Root Kevin T, Batchu Sai, Milanovic Silvija, Ladehoff Lauren, Fadil Angela, Lipner Shari R
Abstract excerpt
OBJECTIVE: Genomic profiling previously classified melanoma into distinct subtypes based on the presence or absence of mutations in driver genes, but metabolic differences between and within these groups have yet to be thoroughly analyzed. Thus, the objective of the present study is to provide the first effort to holistically characterize the metabolic landscape of qualified melanoma genomic subtypes at...
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