Article
Metabolic Alterations and Therapeutic Opportunities in Rare Forms of Melanoma.
Trends in cancer - 1 Aug 2021
Han Anna, Schug Zachary T, Aplin Andrew E
Abstract excerpt
Melanoma is derived from melanocytes located in multiple regions of the body. Cutaneous melanoma (CM) represents the major subgroup, but less-common subtypes including uveal melanoma (UM), mucosal melanoma (MM), and acral melanoma (AM) arise that have distinct genetic profiles. Treatments effective for CM are ineffective in UM, AM, and MM, and patient survival remains poor. As reprogrammed cancer metabolism is...
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