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Article

Prominin-1 Knockdown Causes RPE Degeneration in a Mouse Model

2024-10-10

Abstract excerpt

There are currently no effective treatments for retinal pigment epithelial (RPE) cell loss in atrophic AMD (aAMD). However, our research on Prom1, a known structural protein in photoreceptors (PRs), has revealed its distinct role in RPE and offers promising insights. While pathogenic Prom1 mutations have been linked to macular diseases with RPE atrophy, the broader physiological impact of dysfunctional Prom1 in RP...

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Literature Corpus work
547ebf65-04a7-567a-af7c-6fd83e187ec4
DOI
10.20944/preprints202410.0669.v1
Open publication

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Prominin-1 Knockdown Causes RPE Degeneration in a Mouse ModelDOI 10.20944/preprints202410.0669.v1
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