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Article

661W Photoreceptor Cell Line as a Cell Model for Studying Retinal Ciliopathies

5 Apr 2019

Abstract excerpt

The retina contains several ciliated cell types, including the retinal pigment epithelium (RPE) and photoreceptor cells. The photoreceptor cilium is one of the most highly modified sensory cilia in the human body. The outer segment of the photoreceptor is a highly elaborate primary cilium, containing stacks or folds of membrane where the photopigment molecules are located. Perhaps unsurprisingly, defects in cilia...

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PMID: 31024622
DOI: 10.3389/fgene.2019.00308

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