Article

HTLV-1-Induced Neuroimmunome Correlates with Disease Progression and Severity

2025-09-09

Abstract excerpt

<title>Abstract</title> <p>HTLV-1 infects 10–20 million people globally. While most remain asymptomatic, some develop severe neuroinflammatory or malignant diseases, such as adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Using a systems biology approach, we integrated bulk transcriptomics from PBMCs (n = 200) with single-cell RNA sequencing from 233,0...

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Literature Corpus work: 76b08298-c91f-5649-97a6-a8fdc297e625
DOI: 10.21203/rs.3.rs-7357522/v1

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