Article

RIPK3 Promotes Hantaviral Replication by Restricting JAK-STAT Signaling but not Triggering Necroptosis.

2022-12-06

Abstract excerpt

Hantaan virus (HTNV) is a rodent-borne virus that can cause hemorrhagic fever with renal syndrome (HFRS) with a case fatality rate of 15% and is listed as a re-emerging infectious disease (REID) in China. At present, no specific therapeutic strategies against HTNV are available. Interferon (IFN) is a crucial antiviral molecular which can trigger interferon-stimulated genes (ISGs) expression through the Janus kinas...

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Literature Corpus work: 543ababa-0c6b-506b-beb4-c05b4bbc41a1
DOI: 10.21203/rs.3.rs-2252467/v1

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