Article

The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus

2021-05-13

Abstract excerpt

The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to Old World mammarenavirus, these viruses are not able to completely suppress the innate immune response, and trigger a robust interferon (IFN)-I response via retinoic acid-inducible gene I (RIG-I). Nevertheless, pathogenic NW mammarenaviruses trigger a weaker IFN response...

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Literature Corpus work: 13e250b3-2970-53eb-b8bb-c6fee6459aca
DOI: 10.20944/preprints202105.0297.v1

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