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Inferring the Source of Transmission with Phylogenetic Data

19 Dec 2013

Abstract excerpt

Identifying the source of transmission using pathogen genetic data is complicated by numerous biological, immunological, and behavioral factors. A large source of error arises when there is incomplete or sparse sampling of cases. Unsampled cases may act as either a common source of infection or as an intermediary in a transmission chain for hosts infected with genetically similar pathogens. It is difficult to...

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PMID: 24367249
DOI: 10.1371/journal.pcbi.1003397

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