Article

Inferring the multiplicity of founder variants initiating HIV-1 infection: a systematic review and individual patient data meta-analysis

2021-07-18

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> HIV-1 infections initiated by multiple founder variants are characterised by a higher viral load and a worse clinical prognosis, yet little is known about the routes of exposure through which transmission of multiple founder variants is most likely. <h4>Methods</h4> We conducted a systematic review of studies that estimated founder variant multiplicity in HIV-1 infection, searc...

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Literature Corpus work: e4491819-6a79-5f5d-a690-114de3b8e59b
DOI: 10.1101/2021.07.14.21259809

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