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Identifying genes and pathways linking astrocyte regional specificity to Alzheimer’s disease susceptibility

2022-11-17

Abstract excerpt

Astrocytes have been shown to play a central role in Alzheimer’s Disease (AD). However, the genes and biological pathways underlying disease manifestation are unknown, and it is unclear whether regional molecular differences among astrocytes contribute to regional specificity of disease. Here, we began to address these challenges with integrated experimental and computational approaches. We constructed a human ast...

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Literature Corpus work
543459b3-3119-567f-858e-8a224fffb199
DOI
10.1101/2022.11.16.515390
Open publication

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Identifying genes and pathways linking astrocyte regional specificity to Alzheimer’s disease susceptibilityDOI 10.1101/2022.11.16.515390
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