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Article

Stem cells: The root of prostate cancer?

5 May 2008

Abstract excerpt

The cancer stem cell (CSC) model states that tumors contain a reservoir of self-renewing cells that maintain the heterogeneous cell population of the tumor. These cells appear to be resistant to therapy and can therefore survive to repopulate the tumor during progression to therapy resistant disease. The biology of CSCs is still not definitive since it is difficult to isolate them from solid tumors and analyze...

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PMID: 18459113
DOI: 10.1002/jcp.21489

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