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Article

Targeting Cancer Stem Cells in Castration-Resistant Prostate Cancer

22 Oct 2015

Abstract excerpt

PURPOSE: Clinical evidence suggests increased cancer stem cells (CSCs) in a tumor mass may contribute to the failure of conventional therapies because CSCs seem to be more resistant than differentiated tumor cells. Thus, unveiling the mechanism regulating CSCs and candidate target molecules will provide new strategy to cure the patients. EXPERIMENTAL DESIGN: The stem-like cell properties were determined by a...

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PMID: 26490309
DOI: 10.1158/1078-0432.ccr-15-0190

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