Article

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment

2020-12-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Metastatic castrate-resistant prostate cancer (CRPC) remains uncurable and novel therapies are needed to better treat patients. Aberrant Fibroblast Growth Factor Receptor (FGFR) signaling has been implicated in advanced prostate cancer (PCa), and FGFR1 is suggested to be a promising therapeutic target along with current androgen deprivation therapy. <h4>Methods</h4> We esta...

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Literature Corpus work: 430b441a-41f2-5de7-b67e-a10dd78530f5
DOI: 10.1101/2020.12.13.422586

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