Back to search

Article

The multi-target regulation of cytokine storm by transcription factor Blimp-1

2022-07-26

Abstract excerpt

<h4>Objective: </h4> Cytokine storm syndrome is a fatal condition related to infectious and autoimmune diseases. Here we aim to investigate the regulatory mechanisms of Blimp-1 on cytokine storm. <h4>Methods: </h4> The Blimp1 shRNA was transfected into RAW264.7 macrophages, followed by Toll-like receptor (TLR) ligand stimulation. The mRNA and protein levels of cytokines were detected by real-time PCR and flow cyto...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
53a913c8-4f78-53c4-8474-4219fd07efe9
DOI
10.21203/rs.3.rs-1867845/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The multi-target regulation of cytokine storm by transcription factor Blimp-1DOI 10.21203/rs.3.rs-1867845/v1
Regulation of miRNA in Cytokine Storm (CS) of COVID‐19 and Other Viral Infection: An Exhaustive ReviewSemantic proximity
Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 CellsSemantic proximity
Immunological function of Blimp-1 in dendritic cells and relevance to autoimmune diseases.Semantic proximity
IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1Semantic proximity
Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lungSemantic proximity
Transcription Factor Blimp-1: A Central Regulator of Oxidative Stress and Metabolic Reprogramming in Chronic Inflammatory DiseasesSemantic proximity
Epigenetic Regulation of Inflammatory NF-κB Target Genes by IFN-γ via IRF1Semantic proximity
Analysis of interferon-λ1 gene activation and functionSemantic proximity
IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic MechanismsSemantic proximity
A genome-wide CRISPR screen supported by human genetics identifies the <i>TNRC18</i> gene locus as a novel regulator of inflammatory signalingSemantic proximity
Regulation of dendritic cell activation by microRNA let-7c and BLIMP1.Semantic proximity
Costimulation of TLR8 responses by CXCL4 in Human Monocytes Mediated by TBK1-IRF5 Signaling and Epigenomic RemodelingSemantic proximity
Select a neighboring publication to make it the new centre.