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Article

IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1

6 May 2014

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24796719
DOI: 10.1038/ncomms4770

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Related research

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IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1PMID 24796719Read ↗

Interleukin-27 in T Cell ImmunitySemantic proximity Read ↗

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 CellsSemantic proximity Read ↗

IL-25 Induces IL-4, IL-5, and IL-13 and Th2-Associated Pathologies In VivoSemantic proximity Read ↗

All in the family: IL-27 suppression of TH-17 cellsSemantic proximity Read ↗

IL‐27 controls the development of inducible regulatory T cells and Th17 cells <i>via</i> differential effects on STAT1Semantic proximity Read ↗

Signaling by IL‐12 and IL‐23 and the immunoregulatory roles of STAT4Semantic proximity Read ↗

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathwaysSemantic proximity Read ↗

IL-4 confers resistance to IL-27–mediated suppression on CD4+ T cells by impairing signal transducer and activator of transcription 1 signalingSemantic proximity Read ↗

An overview of IL-17 function and signalingSemantic proximity Read ↗

The biology and therapeutic potential of interleukin 27Semantic proximity Read ↗

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24Semantic proximity Read ↗

Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T CellsSemantic proximity Read ↗

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