Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression.

doi:10.1002/ajmg.b.32503

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Article

Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2016

Whitton Laura, Cosgrove Donna, Clarkson Christopher, Harold Denise, Kendall Kimberley, Richards Alex, Mantripragada Kiran, Owen Michael J, O'Donovan Michael C, Walters James, Hartmann Annette, Konte Betina, Rujescu Dan, Gill Michael, Corvin Aiden, Rea Stephen, Donohoe Gary, Morris Derek W

Abstract excerpt

Epigenetic mechanisms are an important heritable and dynamic means of regulating various genomic functions, including gene expression, to orchestrate brain development, adult neurogenesis, and synaptic plasticity. These processes when perturbed are thought to contribute to schizophrenia pathophysiology. A core feature of schizophrenia is cognitive dysfunction. For genetic disorders where cognitive impairment is...

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Identifiers

PMID: 27762073
DOI: 10.1002/ajmg.b.32503

Genes

CHD7
SATB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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