Article

Rare copy number variants in <i>NRXN1</i> and <i>CNTN6</i> increase risk for Tourette syndrome

2016-07-08

Abstract excerpt

Tourette syndrome (TS) is highly heritable, although identification of its underlying genetic cause(s) has remained elusive. We examined a European ancestry sample composed of 2,435 TS cases and 4,100 controls for copy-number variants (CNVs) using SNP microarrays and identified two genome-wide significant loci that confer a substantial increase in risk for TS ( NRXN1 , OR=20.3, 95%CI [2.6-156.2], p=6.0 × 10 −6 ;...

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Literature Corpus work: 5355ac04-460d-5ed4-be6f-78eb5d7c5a68
DOI: 10.1101/062471

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