Article

Single-cell and spatial landscapes reveal coordinated CD8+ T-cell programs defining responder-specific immune niches in NSCLC

2026-04-19

Abstract excerpt

<title>Abstract</title> <p>Background Reliable biomarkers that explain why only a subset of patients with non-small cell lung cancer (NSCLC) derive durable benefit from immunotherapy remain limited. The tumor immune microenvironment is heterogeneous at both the cellular and tissue-compartment levels. Our aim was to identify reproducible immune programs associated with treatment response by integrating single-cel...

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Literature Corpus work: 53343c48-e36f-5f66-8307-1648af88e95f
DOI: 10.21203/rs.3.rs-9437758/v1

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