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Towards CRISPR-based editing of the mitochondrial genome in yeast

2025-12-09

Abstract excerpt

Mitochondria, which evolved from symbiotic bacteria, possess their own genomes (mtDNA) and support independent transcription and translation within the organelle. Given the essential role of mtDNA in energy production, metabolism, as well as cellular homeostasis, and the high density of confirmed pathogenic mutations that map to mtDNA, there is a pressing need for versatile methods to study and manipulate this gen...

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Identifiers and source

Literature Corpus work
530192c2-42cd-5267-a19e-7bc1bfa942a3
DOI
10.64898/2025.12.09.693232
Open publication

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Towards CRISPR-based editing of the mitochondrial genome in yeastDOI 10.64898/2025.12.09.693232
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