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Article

Can Mitochondrial DNA be CRISPRized: Pro and Contra.

IUBMB life - 1 Dec 2018

Loutre Romuald, Heckel Anne-Marie, Smirnova Anna, Entelis Nina, Tarassov Ivan

Abstract excerpt

Mitochondria represent a chimera of macromolecules encoded either in the organellar genome, mtDNA, or in the nuclear one. If the pathway of protein targeting to different sub-compartments of mitochondria was relatively well studied, import of small noncoding RNAs into mammalian mitochondria still awaits mechanistic explanations and its functional issues are often not understood thus raising polemics. At the same...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 30184317
DOI: 10.1002/iub.1919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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