Article

Identifying branch-specific positive selection throughout the regulatory genome using an appropriate neutral proxy

2019-08-02

Abstract excerpt

Adaptive changes in cis -regulatory elements are an essential component of evolution by natural selection. Identifying adaptive and functional noncoding DNA elements throughout the genome is therefore crucial for understanding the relationship between phenotype and genotype. Here, we introduce a method we called adaptyPhy , which adds significant improvements to our earlier method that tests for branch-specific...

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Literature Corpus work: 52d9bf92-29dd-502e-beba-1d1914bd1cbc
DOI: 10.1101/722884

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