Article
Learning the properties of adaptive regions with functional data analysis.
PLoS genetics - 1 Aug 2020
Mughal Mehreen R, Koch Hillary, Huang Jinguo, Chiaromonte Francesca, DeGiorgio Michael
Abstract excerpt
Identifying regions of positive selection in genomic data remains a challenge in population genetics. Most current approaches rely on comparing values of summary statistics calculated in windows. We present an approach termed SURFDAWave, which translates measures of genetic diversity calculated in genomic windows to functional data. By transforming our discrete data points to be outputs of continuous functions...
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