Article
Detecting natural selection on cis-regulatory DNA.
Genetica - 1 Jan 2007
Hahn Matthew W
Abstract excerpt
Changes in transcriptional regulation play an important role in the genetic basis for evolutionary change. Here I review a growing body of literature that seeks to determine the forces governing the non-coding regulatory sequences underlying these changes. I address the challenges present in studying natural selection without the familiar structure and regularity of protein-coding sequences, but show that most...
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