Article

Estimating the impact of single-cell RNA sequencing of human tissues on drug target validation

2024-04-05

Abstract excerpt

Whilst the use of single-cell RNA sequencing (scRNA-seq) to understand target biology is well established, its predictive role in increasing the clinical success of therapeutic targets remains underexplored. Inspired by previous work on an association between genetic evidence and clinical success, we used retrospective analysis of known drug target genes to identify potential predictors of target clinical success...

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Literature Corpus work: 52d3cecf-2661-5e4f-8d05-031fa18f7170
DOI: 10.1101/2024.04.04.24305313

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