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Single-Cell Transcriptomics Sheds Light on Tumor Evolution: Perspectives from City of Hope’s Clinical Trial Teams

10 Dec 2024

Abstract excerpt

Tumor heterogeneity is a significant factor influencing cancer treatment effectiveness and can arise from genetic, epigenetic, and phenotypic variations among cancer cells. Understanding how tumor heterogeneity impacts tumor evolution and therapy response can lead to more effective treatments and improved patient outcomes. Traditional bulk genomic approaches fail to provide insights into cellular-level events,...

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PMID: 39768430
DOI: 10.3390/jcm13247507

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